Clare Reihill is leaving her role as editorial director of Fourth Estate after more than 10 years with the publisher.
Reihill leaves to work full time at the T S Eliot estate, where she has served as a trustee for for several years.
After starting at Fourth Estate in 2003, Reihill has worked with writers including Joan Didion, Joyce Carol Oates, Amy Tan and Nicola Barker.
Her last day at the HarperCollins imprint will be on January 16th 2015.
The T S Eliot estate is involved with several projects, such as funding the T S Eliot Prize for Poetry, administered by the Poetry Book Society, and the charity Old Possum's Practical Trust.